Security ... think about it!
Even if you have an employee that is not being malicious and truly wants to take the data home to work on it there could still be a major security leak waiting in the wings. If they are taking a piece of secret company data home in their pocket and they go to a bar that people in the industry hang out there could be consequences. What if the employee leaves the USB device there? Then a competitor could get a good portion of your companies secrets.